Panthers Pro Bowl cornerback Jaycee Horn was ruled out of Monday night's game against the 49ers after suffering a concussion late in the first half.

Christian McCaffrey had a big night in his first game against Carolina since the Panthers traded him to San Francisco three years ago.

The Carolina Panthers made their first prime-time appearance in an NFL regular-season game since Nov. 9, 2023, on Monday night with an opportunity to take sole possession of the lead in the NFC South.

San Francisco 49ers receiver Jauan Jennings wasn't approaching Carolina Panthers safety Tre'von Moehrig for a handshake and a hug after his team's 20-9 win on Monday Night Football. Jennings came up to Moehrig and struck him in the face mask with his right hand, then got in a left hand before the two were separated.

Brock Purdy threw three interceptions in the first half, but Carolina only had three points to show for it, and that was the game in a 20-9 49er victory.

The Panthers are unable to punch it in for a touchdown, as running back Chuba Hubbard is stopped on a short pass on third-and-goal from the Niners' 4-yard line. Carolina settles for a 25-yard field goal from kicker Ryan Fitzgerald.

Christian McCaffrey dominated his former Carolina Panthers team as the San Francisco 49ers secured a 20-9 victory on "Monday Night Football," improving to 8-4.

San Francisco receiver Jauan Jennings responded to a cheap shot from Carolina safety Tre'Von Moehrig by throwing a punch after the final whistle.

The San Francisco 49ers are getting ready to take on the Carolina Panthers on Monday Night Football this week, looking to stack consecutive wins for the first time since Week 3. San Francisco is coming off a 41-22 win over the Arizona Cardinals in a game that they dominated from the start,