Get San Francisco vs San Diego baseball betting preview, spread and over/under insights for their matchup on June 2.

The San Diego Padres (33-24) visit the San Francisco Giants (33-26) to open a 4-game series Monday. First pitch from Oracle Park is at 9:45 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Padres vs. Giants odds and make our expert MLB picks and predictions for the best bets.

The Pittsburgh Pirates (22-37) visit the San Diego Padres (32-24) for the final game of their 3-game series. First pitch from Petco Park is at 5:10 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Pirates vs. Padres odds and make our expert MLB picks and predictions for the best bets.

The Padres' need for a left fielder was amplified Sunday after Gavin Sheets crashed face-first into an outfield wall.

The San Diego Padres are reportedly targeting Boston Red Sox outfielder Jarren Duran for a potential trade in exchange for prospects.

The San Diego Padres are targeting Boston Red Sox outfielder Jarren Duran on the trade market, according to Dennis Lin of The Athletic.

Manny Machado homered in the first inning and hit a go-ahead sacrifice fly in a four-run seventh for the San Diego Padres, who rallied past the Pittsburgh Pirates 6-4 to take two of three games in their series.