Cancer metastasis, the spread of cancer to organs, is a major cause of cancer-related deaths. Once cancer spreads to multiple ...

During this trial, activated T-cells were engineered to target disialoganglioside 2 (GD2), a protein often overexpressed in neuroblastoma cells. This therapy involved both activated T-cells (ATCs ...

OX40R is a co-stimulatory molecule expressed on activated effector and memory T cells, and OX40R-positive T cells release pro ...

Participants in the study, which enrolled from 2004 to 2009, were infused with two immune effector cell products -- activated T cells expanded with OKT3 antibody and Epstein-Barr virus (EBV ...

Results at a three-year median follow-up, now published, show: The investigational cancer vaccine activated a T cell response in half of patients (responders), and this response correlated with ...

Given these promising results and a strong scientific rationale, combined with LX-101’s novel mechanism of action and prior positive clinical experience in oncology, Lirum is planning new clinical ...

Researchers associated with the New York-based Memorial Sloan Kettering Cancer Center have obtained positive results in the Phase 1 clinical trial of an experimental vaccine.