Cattle that are vaccinated with the BCG vaccine, which contains a harmless strain of the bovine TB pathogen Mycobacterium bovis, produce a positive PPD test for TB making it impossible to ...

BCG, a century-old vaccine for tuberculosis, is in the news, raising hopes for the COVID-19 pandemic. But existing ecological studies have serious limitations. Randomized trials are urgently needed.

ImmunityBio has gained US Food and Drug Administration (FDA) authorisation for an expanded access programme to supply an alternative source of Bacillus Calmette-Guerin (BCG) to treat bladder ...

Bacillus Calmette-Guérin (BCG) vaccine—named for its developers—contains inactivated mycobacteria that infect cattle and remains the only vaccination strategy against the infection in humans.

Female C57BL/6 mice were inoculated intraperitoneally (i.p.) with 10 6 colony-forming units (CFU) of the BCG strain harboring an empty plasmid (BCG(e)) one month before i.n. immunization with Ad ...

Howard Hughes Medical Institute investigator William R. Jacobs and colleagues have produced a genetically altered strain of tuberculosis, that elicits a stronger immune response than the current ...

Restoration of genes lost during the original attenuation of the commonly used BCG tuberculosis vaccine enhances the ability of a recombinant strain to protect against Mycobacterium tuberculosis.