Nucleases degrade DNA molecules by breaking the phosphodiester bonds that link one nucleotide to the next in a DNA strand. There are two distinct kinds of nucleases: - Exonucleases, which remove ...

Traits as diverse as the color of a person's eyes and the scent of a rose are determined by the information contained in DNA. Learn how this information is coded by strings of molecules called ...

Ribonucleic acid (RNA) is a linear molecule composed of four types of smaller molecules called ribonucleotide bases: adenine (A), cytosine (C), guanine (G), and uracil (U). RNA is often compared ...

TComparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases (Image: Wikimedia Commons, CC SA 3.0) The nucleotides are connected through phosphodiester bonds, ...

My scientific interests center on nucleases, a functionally diverse class of enzymes that catalyze the cleavage of phosphodiester bonds to support a wide breadth of pathways, including DNA replication ...