(SALT LAKE CITY)—Dicer, an enzyme essential for life, cleaves long double-stranded RNA (dsRNA) into short pieces that regulate gene expression. But in many ways dsRNA molecules all look alike, and ...
How an enzyme, appropriately named DICER, cuts double-stranded RNA to produce short sections of RNA that regulate genes has been revealed. Small snippets of RNAs can turn off genes, stopping them from ...
Diana Maltseva, at el. Incautious design of shRNAs for stable overexpression of miRNAs could result in generation of undesired isomiRs, Biochimica et Biophysica Acta (BBA) — Gene Regulatory Mechanisms ...
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