The cell's endoplasmic reticulum (ER) plays a central role in protein synthesis, folding, and calcium (Ca²⁺) storage. When damaged, ER-phagy (self-eating) removes affected ER regions via ...

(Siarhei_Fetisenkov/Creatas Video+/Getty Images Plus) An eagerly awaited and controversial clinical trial to 'wind back the ...

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these added golden years are not spent in good health. Aging is a natural part of ...

The endoplasmic reticulum (ER) employs a diverse proteome landscape to orchestrate many cellular functions, ranging from protein and lipid synthesis to calcium ion flux and inter-organelle ...

The experimental treatment, known as ER-100, is being tested in patients suffering from glaucoma and other forms of ...

Scientists found that aging may begin with a hidden cellular remodel that could help drive disease later in life.

The body's cells change their shape to close gaps such as wounds – with part of the cell flexing depending on the curve of the gap and the organization of cell-internal structures, a new study reveals ...

Many physicochemical properties in the cellular milieu are important for cell function and survival. However, the polarity of different subcellular compartments and its role in protein condensate and ...

Caption The ER (in yellow) almost covers the entire expanse of a cell. (left) Tube-like ER structure at the cell periphery near a convex shaped gap boundary; (right) Flattened sheet-like ER structure ...

Results overturn assumptions about the body's primary structural building block, opening potential new avenues for treating fibrosis and cancer.