The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to transport ...

we describe the 1.9 Å resolution structure of E. coli FhuD in complex with gallichrome. FhuD adopts a novel fold and represents a new class of iron binding ABC-type transport proteins.

Cytochrome P450 (CYP) proteins are responsible for breaking down more than 80% of all Food and Drug Administration ...

Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that it is much more dynamic than previously thought.

However, mutations in the spike protein can alter its structure ... Short Peptide Inhibiting ACE2 binding (CeSPIACE), a ...

Inhibitors that target binding pockets that affect kinase activation loop conformation, interfere with substrate binding or modulate protein ... potent but the known structure–activity ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...

Researchers have uncovered the 3D structure of RBP3, a key protein in vision, revealing how it transports retinoids and fatty ...

Array Bridge is testing promising drug candidates that can effectively bind and even degrade target proteins, but not via ...