New research has settled the debate between ‘kiss-and-run’ and ‘full-collapse’ fusion to explain how neurons transmit signals across synapses. Scientists from the University of Science and Technology ...
For decades, neuroscientists have debated whether synaptic vesicles “kiss-and-run” or do an irreversible “full collapse” when releasing neurotransmitters. Now, a team in China has frozen that moment ...
A millisecond-precision time-resolved cryo-ET system, combining plunge-freezing with optogenetic stimulation (top left), captured distinct intermediate states of SV exocytosis in intact hippocampal ...