The American Society of Regional Anesthesia and Pain Medicine has published a practice advisory on local anesthetic systemic toxicity (LAST) called “Guidelines for the Management of Severe Local ...

Our results suggest that ultrasound guidance, HBV infection and the female sex are risk factors of LAST in LPBs and SNBs. For patients infected with HBV or female patients undergoing LPBs and SNBs, ...

Over the last decade, poisonings and deaths linked to the use of local anesthetics have decreased. Even so, poisonings from one commonly used anesthetic, lidocaine, have increased in the United States ...

One lot of Lidocaine HCl Topical Solution 4%, 50ml has been recalled by Teligent Pharma after company-testing found it to be super potent. As the Teligent-written, FDA-posted recall notice states, ...

For the second time in just over six weeks, Teligent Pharma recalled Lidocaine HCl Topical Solution 4%, 50ml for super potency. This time, instead of just one lot, Teligent pulled five lots, four ...

There was a decrease noted in reports of death in the operating room, from 47% before 2010 to 15% after 2010 in a case analysis. HealthDay News — Local anesthetic poisoning reports decreased following ...

Teligent Pharma has voluntarily recalled two lots of Lidocaine HCl Topical Solution USP 4% because testing found it to be “super potent.” People could be using a higher than intended dose of the ...

Local anesthetics should only be administered by clinicians who are well versed in diagnosis and management of dose-related toxicity and other acute emergencies which might arise from the block to be ...