Narcolepsy, with or without cataplexy, can have a substantial detrimental effect on well-being and quality of life. Because there is no cure for this condition, current treatments aim to improve ...

Pitolisant (Wakix) in children ages 6 years and up led to clinically meaningful improvements in narcolepsy symptoms in a phase III trial. Among 110 kids with narcolepsy with or without cataplexy, ...

Narcolepsy was linked to high blood pressure, hyperlipidemia, and diabetes on top of outright cardiovascular disease events in a retrospective cohort study. Notably, patients with narcolepsy started ...

Pitolisant is now the only treatment option not scheduled as a controlled substance that is indicated for both excessive daytime sleepiness and cataplexy in pediatric and adult patients. The Food and ...

Please provide your email address to receive an email when new articles are posted on . Most participants with narcolepsy with cataplexy who took the sodium oxybate therapy Xyrem at the beginning of a ...

Narcolepsy is a neurological disorder that is characterized by excessive daytime sleepiness and cataplexy—a loss of muscle tone generally triggered by certain strong emotions with sudden onset. The ...

Lupin has received tentative approval from the Food and Drug Administration for pitolisant tablets, 4.45 mg and 17.8 mg. The ...

Cataplexy, or sudden muscle weakness that can resemble fainting, may be prompted by strong emotions. This symptom isn't serious and mostly occurs with narcolepsy type one — otherwise, it's very rare.

Lower-sodium oxybate (LXB) and sodium oxybate (SXB) were proven equally effective for cataplexy and excessive daytime sleepiness (EDS), despite LXB having 92% less sodium. For patients with cataplexy ...

Topiramate May Be Effective for Alcohol Use Disorder, PTSD Symptoms Sodium oxybate (Xyrem; Jazz), alone or in combination with modafinil, improved excessive sleepiness in patients with narcolepsy both ...

For years, Julie Flygare kept her condition private. She hadn’t liked people’s reactions on the occasions when she had opened up and shared her story. People thought it was a joke or not important. In ...