Hormone-regulated immune cells produce IL-10 to resolve pain more effectively in males, offering a potential new target for non-opioid chronic pain treatments.

An intense description of suffering arrived in a mailing from an expressive arts gallery: My arms reach upward as the mind and hair are disintegrating, reaching through burning into the light.

Women suffer more. But why? A new study points to an immune mechanism that differs between women and men, which may affect the duration of pain after trauma.

A study in Science Immunology reveals an immune mechanism influenced by hormones that may explain why chronic pain persists ...

Women are more likely to experience chronic pain, studies have found, and their pain lasts longer, on average. New research suggests it's because of immune system differences.

Cells lining the mouse colon. L cells, which produce PYY, are shown in green; serotonin producing EC cells in magenta; cell cytoskeleton in yellow. Women are dramatically more likely than men to ...

Chronic pain lasts longer for women than men, and new research suggests differences in hormone-regulated immune cells, called ...

Chronic pain lasts longer for women than men, and new research suggests differences in hormone-regulated immune cells, called monocytes, may help explain why. In a new paper in Science Immunology , ...

Researchers say collective results highlight the therapeutic potential of enhancing IL-10+ monocytes for treating sex-biased pain conditions.