Study finds that large embryo cells divide step by step using a mechanical ratchet system, challenging the textbook idea of a ...

Figure 1: A fluorescence image of an induced presomitic mesoderm (iPSM) tissue model, where cells expressing the Hes7 gene—a key regulator of somite formation—are labeled green. Purple cells express a ...

Scientists have uncovered a surprising new way that giant embryonic cells divide—without relying on the classic “purse-string” ring long thought essential for splitting a cell in two. Studying ...

S. Piccolo, Y. Sasai, B. Lu, E.M. De Robertis, "Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4," Cell, 86:589-98, 1996. (Cited in more than 170 ...

Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology. Pluripotent stem cells (PSCs) have been invaluable ...

New stem cell-based embryo model reveals previously unknown communication between early tissues that become the spine and muscles in the central part of the body. From the moment an embryo starts to ...

A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus. “They are not identical,” said Magdalena Zernicka-Goetz, a ...