With the loss Buffalo is now 7-4. Their hopes of catching the New England Patriots in the AFC East are getting slimmer. The good news is that they currently hold the No. 6 seed in the AFC as a crowded field in the hunt—including the now 6-5 Texans—give chase.

The Buffalo Bills fell short to the Houston Texans on "Thursday Night Football," dropping their 2025 record to 7-4. It didn't take long for fans to assign blame for this upset loss. Houston's defense was dominant all night long against Buffalo,

The Buffalo Bills will visit the Houston Texans at NRG Stadium on "Thursday Night Football" with a big win on the line. For this AFC battle between Sean McDermott's Bills (7-3) DeMeco Ryans' Texans (5-5), it will be the games, within the game, that will make all the difference.

Forced into entrusting backup quarterback Davis Mills to save their entire season, the Houston Texans have discovered that letting a seriously elite defensive unit feast makes perfect sense, which truly showed itself during their latest victory over the Buffalo Bills.

Coming off a 44-point offensive explosion, the Bills now face the Texans' league-best defense. Here's a look ahead to the Thursday night game.

Houston quarterback C.J. Stroud is still recovering from a concussion and will miss a third straight game when the Texans host the Buffalo Bills on Thursday night.