Although previously thought to be neutral, research in yeast suggests that synonymous point mutations may have strongly nonneutral effects. A group of researchers from the University of Michigan (MI, ...

Myeloid leukemias are among the most aggressive blood cancers and have low survival rates. Today, leukemia patients undergo ...

Researchers found a way to screen cancer-linked gene mutations much more easily and quickly than existing approaches, using a variant of CRISPR genome-editing known as prime editing. Tumors can carry ...

In a recent study posted to the bioRxiv* pre-print server, researchers proposed a structural mechanism to explain immune evasion effects of the two-point mutations, S371L and S371F, in the ...

Researchers have pinpointed what could be the early genetic origins of breast cancer -- cancer-like mutations appearing in the cells of healthy women. In a new study, the international collaborators ...

Investigations suggest V2P may be efficiently applied for the automated identification of causal variants in simulated and actual patient sequencing data across phenotypes.