Virginia (8-1, 5-0 ACC) is a 6.5-point favorite in the matchup with Wake (5-3, 2-3 ACC), which is coming off a 42-7 loss at Florida State last week.

The Cavaliers are -255 to win with the over/under set at 48.5 points, alluding to how UVA has been winning games by relying on its defense recently. I’ve got Virginia winning, but not covering with a 24-20 victory.

The No. 15 Virginia Cavaliers face the California Golden Bears on Saturday, Nov. 1, 2025 at California Memorial Stadium in Berkeley, Calif.

The Virginia offense got back on track in Saturday’s 31-21 win at Cal, even if it left some points on the field.

College football Week 11 odds, picks, predictions, TV channel, streaming for Wake Forest Demon Deacons vs Virginia Cavaliers ACC game on Nov. 8, 2025.

After averaging 3.6 wins in his first three seasons at Virginia, Tony Elliott has the Cavs at 7-1 and ranked No. 15 nationally.