Researchers identify the anterior insula as the brain region responsible for biasing decisions toward alcohol over social rewards in addiction.

New research suggests the weight-loss medications could be powerful tools in tackling substance use disorders.

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

For years, addiction was seen as a matter of personal failure—a bad habit or a lack of discipline. People believed those who struggled with substance abuse could stop if they simply wanted to. But ...

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...

Evidence is mounting that the wildly popular weight-loss medicines known as GLP-1s may also hold potential for treating addiction, and the field may be on the verge of obtaining desperately needed ...

The brain is a master controller, organized into large-scale neural networks that directly affect whether people with addictions break free or surrender. Research has identified a key site, the action ...

What is addiction, and how can we stop it? The complexities of addiction have stumped scientists for decades. Today, with 48 million Americans over the age of 12 suffering from a substance use ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...