Cancer Res (2023) 83 (8_Supplement): LB321. Citation Format: Elizabeth Donohue Vo, Yang W. Zhang, Dave Rominger, Jillian M. Silva, Yang J. Zhang, Greg Lee, John ...
ActA mediates cross-talk between breast cancer cells and cancer-associated fibroblasts in the lung metastatic niche that enhances fibrosis and metastasis, implicating ActA as a potential therapeutic ...
Cancer Res (2024) 84 (6_Supplement): 48. Introduction: Multiple Myeloma (MM) is the second most diagnosed hematologic malignancy and remains an incurable disease. KLN-1010 is a novel treatment for MM ...
Cancer Res (2023) 83 (8_Supplement): LB329. Methods: Cellular potency of ABSK021 was evaluated by Celltiter-Glo assay in osteosarcoma cell lines and CSF-1R expression was evaluated by western blot. In ...
In MTAP-deficient cancer cells, PRMT5 expression and activity is preferentially required for cell growth. Major finding: In MTAP-deficient cancer cells, PRMT5 expression and activity is preferentially ...
Cancer Res (2021) 81 (13_Supplement): 1261.
Cancer Discov (2026) 16 (1): OF1.
Abstract. AZD9833 is a potent, orally delivered, non-steroidal selective estrogen receptor degrader (SERD) that both antagonizes and degrades ERα. It is currently in clinical testing for the treatment ...
Abstract. Binding of steroid hormones to their cognate receptors regulates the growth of most prostate and breast cancers. We hypothesized that CYP11A inhibition might halt the synthesis of all ...
The discovery and characterization of novel WRN helicase inhibitors provides pharmacological validation for the clinical development of WRN inhibitors for the treatment of patients with MSI tumors.
Institute of TCM-X/MOE Key Laboratory of Bioinformatics, Bioinformatics Division, BNRist/Department of Automation, Tsinghua University, Beijing, China.
1Yonsei University, College of Medicine, Seoul, Republic of Korea.
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