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Findings from a phase I/II trial provide clinical proof-of-concept for a first-in-class mRNA-encoded T-cell engager targeting CLDN6 and CD3. Produced in vivo, the bispecific was well tolerated and had ...

1Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. 2Department of Radiation Oncology, Harbin Medical University Cancer Hospital, Harbin, ...

1Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas. *Corresponding Author: Guillermina Lozano, Department of Genetics, The University of Texas MD Anderson ...

Radiation Research Program, Division of Cancer Treatment and Diagnosis, NCI, Bethesda, Maryland. *Corresponding Author: Jeffrey C. Buchsbaum, Radiation Research Program, Division of Cancer Treatment ...

*Corresponding Author: Mara H. Sherman, Cancer Biology & Genetics, Memorial Sloan Kettering Cancer Center, 417 East 68th Street, 1261, New York, NY 10065. E-mail: [email protected] ...

1Department of Population Health Sciences, Weill Cornell Medicine, New York, New York. 2Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York. *Corresponding Author: Kevin ...

According to a newly published article, immune cells with a loss of the Y chromosome (LOY) are less equipped to attack cancer cells than their Y chromosome-containing counterparts (Nature 2025 Jun 4 ...

Drug companies are pouring billions of dollars into PD-1×VEGF bispecific antibodies, hoping these dual-action drugs can outperform existing immunotherapy and anti-angiogenic combinations in lung ...