She noted that the SWOG Cancer Research Network has competed a trial using a Tokyo-172 strain of BCG, comparing it with the TICE strain, and if this trial shows noninferiority, it will offer more ...

ImmunityBio has gained US Food and Drug Administration (FDA) authorisation for an expanded access programme to supply an ...

Female C57BL/6 mice were inoculated intraperitoneally (i.p.) with 10 6 colony-forming units (CFU) of the BCG strain harboring an empty plasmid (BCG(e)) one month before i.n. immunization with Ad ...

Restoration of genes lost during the original attenuation of the commonly used BCG tuberculosis vaccine enhances the ability of a recombinant strain to protect against Mycobacterium tuberculosis.

The new BCG vaccine strain has been found to protect mice against tuberculosis significantly better than the parental BCG. Superior protection is not only induced against the laboratory strain ...

Older versions of the BCG vaccine may be better at preventing cases of tuberculosis than more commonly used modern vaccines, say French scientists. Genetic changes in strains over the years have ...

It is based on the well-known Mycobacterium bovis (M. bovis) Bacillus Calmette-Guérin (BCG) strain. It has been in use since 1921 and administered to more than 4 billion individuals worldwide.

“We hope that this ‘kill switch’ BCG strain could limit safety concerns over intravenous vaccine administration and provide an option for a safer and more effective vaccination route for ...

Currently, no country in the world uses vaccination to control bovine TB, even though the BCG vaccine has been in use since 1921 to prevent the disease in children. Diva test ‘vital’ ...

ImmunityBio has gained US Food and Drug Administration (FDA) authorisation for an expanded access programme to supply an alternative source of Bacillus Calmette-Guerin (BCG) to treat bladder ...