NMDAR antibodies are present in serum and CSF, usually with intrathecal synthesis, and are sometimes only detected in the CSF. The main target epitopes are in the NR1/NR2 heteromers of the NMDAR.

The current patient presented with low-grade fevers, headaches and anxiety that progressed to paranoia, homicidal ideation, and seizures. These symptoms suggested several toxic and metabolic ...

Ma2 is an autoantigen previously identified in patients with germ cell tumours of the testis and paraneoplastic brain stem and limbic encephalitis. Our patient's clinical and immunopathological ...

Clinicians should consider this treatable disorder in the differential diagnosis of vCJD. CSF, cerebrospinal fluid MRI, magnetic resonance imaging PLE, paraneoplastic limbic encephalitis vCJD, variant ...

Figure 2 Magnetic resonance imaging findings in paraneoplastic limbic encephalitis. There is increased signal intensity in the medial aspect of the temporal lobes. In (A), The more intense signal in ...

Paraneoplastic antibodies were detected in 10 patients ... The treatment and prognosis of 19 patients with encephalitis, aseptic meningitis, or meningoencephalitis are summarized in Table 3. All ...

Keywords: autoimmune encephalitis, biomarkers, immune-mediated neurological disorders, paraneoplastic syndromes, post-infectious autoimmunity, molecular mechanisms, therapeutic strategies, genetic ...

in whom NMDA-receptor and LGI1 antibody encephalitis are the dominant syndromes, followed by a broad array of other cell surface and paraneoplastic autoantibodies. 1 Future revisions to the diagnostic ...

indicated a possible immunologic cause supporting the diagnosis of autoimmune encephalitis syndrome.2 Although this disorder is more commonly associated with antibodies to neuronal cell ...

Nov. 3, 2023 — Researchers have pioneered a novel treatment for the most common autoimmune encephalitis. By reprogramming white blood cells to target and eliminate ... The Quail Could Be the ...

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