The discovery could help create new "sensorially appealing foods" that improve digestion and feelings of fullness.

Looking for more films like 'The Substance'? Meg Shields has a few suggestions, from high camp classics to gnarly body horror.

Demi Moore photographed in Los Angeles on Mar. 21Adrienne Raquel for TIME This story is part of the 2025 TIME100. Read Ryan ...

Substance use and misuse affect people from all backgrounds and age groups. A substance use disorder occurs when there is recurrent use of a substance that affects a person's daily life. Substance use ...

"Harm reduction" interventions for substance use—measures like needle exchange programs and methadone distribution that aim ...

Mice lacking two neuropeptides thought to be essential for processing pain show no change in how they respond to a wide range of harmful stimuli.

Bill 53 would help individuals who are a danger to themselves or others due to their substance use or addiction get on the path to recovery.

A cup of coffee is a key part of most people’s morning routine but a new study has outlined a surprise risk. A new study has ...

The Substance’s Demi Moore, who was the predicted frontrunner for Best Actress at last month’s Oscars ceremony, detailed how she knew Anora’s Mikey Madison would win the trophy.