President Donald Trump issued a new social media proclamation Sunday night directing federal officials to prioritize deportations from New York and other Democrat-run cities, a move that comes after large protests erupted across the country in response to his administration’s immigration enforcement policies.

President Donald Trump directed federal officials to expand efforts to deport migrants in the largest US cities in the face of protests and court challenges, even as his administration is looking to ease the impact of the crackdown on key sectors of the American workforce.

"No Kings" protests against the Trump administration are taking place today in and around New York City as part of nationwide demonstrations. Fifth Avenue was closed to traffic from 42nd Street to 23rd Street in Manhattan as protesters marched from Bryant Park.

New York City officials are outlining safety plans Friday as they prepare to secure protests expected to pop up in the five boroughs as part of a national No Kings day of action against the Trump administration.

The NYC demonstrations are expected to be part of the largest nationwide protest of President Trump's second term. CBS News New York's Kristie Keleshian reports.

The Trump administration has paused immigration raids targeting farm and hotel workers, but the president has called for more ICE raids in cities.

President Donald Trump vowed Monday to focus his immigration crackdown on so-called “crime ridden inner cities” like New York after he ordered an end to controversial workplace raids on farms, restaurants and hotels amid complaints from big businesses.