This innovative software, CRISPRware, optimizes guide RNA design for genome editing, supporting research on genetic disorders ...

A Ph.D. student in biomolecular engineering at the University of California, Santa Cruz, has built a software program ...

CRISPR is revolutionizing medicine by enabling precise DNA edits, treating genetic diseases like sickle cell anemia and ...

Explained: In a first, how a customised gene-editing tool was used to treat 9-month-old boy In 2012, scientists Jennifer Doudna and Emmanuelle Charpentier replicated this mechanism found in microbes ...

IscBs are a type of OMEGA system, the evolutionary ancestors to Cas9, which is part of the bacterial CRISPR system that Zhang and others have developed into powerful genome-editing tools.

In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long endeavor reached fruition in the form of a new treatment, CASGEVY, approved by ...

Engineered protein mutations may be exploited to tune molecular interactions in the cellular environment. Here, we have explored the structural consequences of different Cas9 mutations in ...

No patients have received Casgevy, CRISPR Therapeutics and Vertex Pharmeceuticals’ recently approved sickle cell gene therapy. Experts weigh in on the path to profit for the treatment and the ...

As the yearslong litigation over ownership of CRISPR gene editing continues, investors have forged ahead with funding the technology’s development by biopharma. CRISPR-Cas9 technology has been ...

How has CRISPR been used? What are potential risks of CRISPR? CRISPR, short for CRISPR-Cas9, is a genome-editing tool that allows scientists to precisely cut and modify DNA sequences.