Structure of mRNA initiation complex could give insight into cancer and other diseases. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2020 / 09 / 200903145025.htm.

By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

Nakayama, H., et al. (2022) Liquid Chromatography−Mass Spectrometry-Based Qualitative Profiling of mRNA Therapeutic Reagents Using Stable Isotope- Labeled Standards Followed by the Automatic ...

The popularity of mRNA-based therapeutics has surged over the past few years. To ensure the safety of these treatments, scientists need to analyze the characteristics of the manufactured molecules, ...

In contrast, the mRNA of eukaryotic organisms is prepared for translation through more complex mechanisms. For one, the addition of a guanine nucleotide with a methyl (CH 3) group to the 5' end of ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

The team used an mRNA that lacked a start codon so that it would be trapped in the act of scanning. While big for a biological machine, you could fit about 3,000 of these complexes across the width of ...

When the COVID-19 pandemic swept across the world in 2020, the mRNA vaccines came to the rescue of many people—but in the ...

Plausible mechanisms of mRNA degradation include (i) dissociation of PM structure by polyion exchange reaction with anionic biomolecules in serum to release mRNA, followed by RNase attack and (ii ...

When the final Phase 3 data came out last November showing the mRNA vaccines made by Pfizer/BioNTech and Moderna were more than 90% effective, Dr. Anthony Fauci had no words. He texted smiley face ...

We asked experts about how the technology works, its safety and its potential in medicine. By Nina Agrawal Health Secretary Robert F. Kennedy Jr. has repeatedly questioned the safety of mRNA ...