Viktor Gyokeres leads the line for Arsenal, finally making his Premier League debut despite spending four seasons at Brighton and Hove Albion earlier in his career. He is not the only fresh face in the Gunners' lineup, though, with Martin Zubimendi slotting into a place in midfield. See Arsenal's starters and substitutes below.

Manchester United take on Arsenal in the headline clash of the opening Premier League weekend. Ruben Amorim’s side host one of their historic rivals at Old Trafford, with both sides desperate to start strongly.

Manchester United is 102-51-90 against Arsenal, though they lost and drew with the Gunners in league play last season. Time: 11:30 a.m. ET Where: Old Trafford (Manchester, U.K.)