South San Francisco, CA, Nov. 14, 2024 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutes dedicated to regenerative medicine, marked a historic ...
BACKGROUND: The regulation of gene expression is complex and occurs at many levels, including transcriptional and post-transcriptional, in metazoans. Transcriptional regulation is mainly determined by ...
脑肿瘤（BT）无论是起源于大脑还是从其他部位扩散到大脑，都是无法治愈的。 尽管手术、放射、药物和基因疗法取得了进展，但 BT 的生存率仍然很低。 目前的治疗方法受到限制，因为它们 ...
听力损失是美国主要的出生缺陷，每 3 名出生的儿童中约有 1,000 名患有部分至严重的听觉功能受损。据估计，约 4% 的 45 岁以下人群和 34% 的 65 岁及以上人群受到衰弱性听力损失的影响。
尽管有充分的证据表明中枢神经系统祖细胞库对创伤性脑损伤有反应，但所报告的影响是可变的，并且可能有助于恢复和病理生理学。通过更好地了解成人大脑中不同的祖细胞群及其对创伤性 ...
Nous avons utilisé nos ressources pour créer une stratégie de thérapie antirétrovirale (TAR) efficace chez des souris humanisées afin d'imiter le traitement TAR chez l'homme afin de faciliter ...
En raison de la durabilité et de la persistance des réservoirs de cellules infectées par le VIH-1, la thérapie antirétrovirale combinée (TAR) est insuffisante pour éradiquer l'infection. Parvenir à la ...
Cell-based immunotherapy has become the new-generation cancer medicine, and "off-the-shelf" cell products that can be manufactured at large scale and distributed readily to treat patients are ...
Yan-Ruide Li, Samuel Zeng, Zachary Spencer Dunn, Yang Zhou, Zhe Li, Jiaji Yu, Yu-Chen Wang, Josh Ku, Noah Cook, Adam Kramer, Lili Yang Allo-HSCT is a curative therapy for hematologic malignancies ...
Engineering stem cells presents an attractive paradigm for cancer immunotherapy. Stem cells engineered to stably express various chimeric antigen receptors (CARs) or T-cell receptors (TCRs) against ...
It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and ...
Natural bypass arteries, i.e. collaterals, can improve the prognosis in patients with occlusive artery disease. Unfortunately, some patients never develop identifiable collaterals. However in animal ...
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