Case Study 188: Addison’s Disease This rare endocrine disorder occurs when the adrenal glands don’t produce enough cortisol and aldosterone. Patients often present with fatigue, weight loss, low blood pressure, salt cravings, and even skin hyperpigmentation, especially in the creases of the hands or inside the mouth. It’s often misdiagnosed until a crisis hits. Diagnosis involves checking ACTH and cortisol levels, followed by an ACTH stimulation test. Treatment includes lifelong hormone replacem
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PPID, or Pituitary Pars Intermedia Dysfunction, is a progressive endocrine disorder that affects the horse’s pituitary gland — the small but mighty control center for hormones. Over time, nerve degeneration in the hypothalamus causes the pituitary to overproduce ACTH, which in turn spikes cortisol levels throughout the body. That hormonal imbalance can impact everything from immune function and energy regulation to metabolism and hoof health. It’s why horses with PPID often grow long, wavy coats
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