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🌱 Precauciones La administración concomitante de hipérico e indinavir (inhibidor de la proteasa) reduce de forma significativa las concentraciones plasmáticas de este medicamento, probablemente debido a la inducción del isoenzima 3A4 del citocromo P450 por algún componente del hipérico, lo que puede producir fallo terapéutico en pacientes seropositivos. •Además, si se estás tomando hipérico de forma concomitante con otros medicamentos y deja de administrarse el hipérico, puede producirse un aum
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